Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA544449

Invitrogen™ TMEM110 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA544449
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA544449 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA544449 Supplier Invitrogen™ Supplier No. PA544449
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Peptide sequence: MQGPAGNASR GLPGGPPSTV ASGAGRCESG ALMHSFGIFL QGLLGVVAFS Sequence homology: Human: 100%; Rabbit: 100%; Rat: 86%.

Acts as a regulator of store-operated Ca(2+) entry (SOCE) at junctional sites that connect the endoplasmic reticulum (ER) and plasma membrane (PM), called ER-plasma membrane (ER-PM) junction or cortical ER (PubMed:26322679, PubMed:26644574). SOCE is a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:26322679). Acts by interacting with STIM1, promoting STIM1 conformational switch (PubMed:26322679). Involved in STIM1 relocalization to ER-PM junctions (PubMed:26644574). Contributes to the maintenance and reorganization of store-dependent ER-PM junctions (PubMed:26644574). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM110
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene STIMATE
Gene Accession No. Q86TL2
Gene Alias 1810038N08Rik; 2310014H19Rik; AW554125; STIM-activating enhancer; STIM-activating enhancer encoded by TMEM110; STIMATE; Store-operated calcium entry regulator STIMATE; Tmem110; Transmembrane protein 110
Gene Symbols STIMATE
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human TMEM110 (aa 1-50).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 375346
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.