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Invitrogen™ TMEM16B Polyclonal Antibody
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Catalog No. PIPA520842
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100 μg
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Catalog No. Quantity
PIPA520842 100 μg
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Catalog No. PIPA520842 Supplier Invitrogen™ Supplier No. PA520842
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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-20842 can be used with blocking peptide PEP-0956.

Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC's but has different biophysical characteristics such as voltage dependence and unitary conductance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM16B
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Ano2
Gene Accession No. Q8CFW1, Q9NQ90
Gene Alias ANO2; anoctamin 2; anoctamin 2 isoform Adelta4; anoctamin 2 isoform Bdelta4; anoctamin 2, calcium activated chloride channel; anoctamin 2-like; anoctamin-2; BC033409; C12orf3; LOC100361584; Tmem16b; Transmembrane protein 16B; transmembrane protein 16B (eight membrane-spanning domains)
Gene Symbols Ano2
Host Species Rabbit
Immunogen A 19 amino acid peptide from near the amino terminus of human TMEM16B.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100361584, 243634, 57101
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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