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Tmem18 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981677
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50-198-1677 100 μL
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Catalog No. 50-198-1677 Supplier Bioss Supplier No. BS11799R
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Description

Rabbit Polyclonal Antibody

Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.

Specifications

Antigen Tmem18
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TMEM18
Gene Accession No. Q96B42
Gene Alias BC024093; TMEM18; Transmembrane protein 18
Gene Symbols TMEM18
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Tmem18.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 129787
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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