Invitrogen™ TMEM184A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596834

Catalog No. PIPA596834

Description

Immunogen sequence: FPCQVYAEKK ENSPAPPAPM QSISSGIRET VSPQDIVQDA IHNFSPAYQH YTQQATHEAP RPGTHPSGGS GGSRKSRSLE KRMLIPSEDL; Positive Samples: Mouse lung, Mouse liver, Mouse kidney, Rat lung; Cellular Location: Membrane, Multi-pass membrane protein.

TMEM184A, a multi-pass transmembrane protein, belongs to the UPF0206 family. While the exact function of TMEM184A remains unclear, it is known to be expressed at high levels in the developing testis. TMEM184A may mediate sex-specific signaling events during Sertoli cell differentiation. The restricted expression of this gene in Sertoli cells suggests a role for the encoded protein in the development and/or continued function of that cell type. Ectopic expression of TMEM184A in female genital ridges resulted in failure of gonocytes to enter meiosis.

Specifications

• Antigen: TMEM184A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM184A
• Gene Alias: RGD1306702; Sdmg1; Sexually dimorphic expressed in male gonads 1; tcag7.540; TMEM184A; Transmembrane protein 184A
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 231832, 304325
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.49 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3UFJ6, Q4QQS1
• Gene Symbols: TMEM184A
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 324-413 of human TMEM184A (NP_0010910891).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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