Invitrogen™ TMEM184C Polyclonal Antibody

Catalog No.	Quantity
PIPA562896	100 μL

Catalog No. PIPA562896 Supplier Invitrogen™ Supplier No. PA562896

Description

Rabbit Polyclonal Antibody

Immunogen sequence: LSSSSQDAIS IASSMPPSPM GHYQGFGHTV TPQTTPTTAK ISDEILSDTI GEKKEPSDKS VD Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 40%.

Anaplastic thyroid cancer is one of the most lethal forms of cancer, but the precise carcinogenic mechanism has not been identified. TMEM184C, also known as TMEM34, was identified in a cDNA microarray analysis as being down-regulated in anaplastic thyroid cancers compared to normal thyroid tissues. TMEM184C protein expression was also lower in cell lines derived from these types of cancers compared to that of normal thyroid tissues or cell lines based on other types of thyroid cancers. Furthermore, transfection of TMEM34 into KTA2 cells led to the inhibition of cell growth, suggesting that TMEM184C might act as a tumor suppressor in anaplastic thyroid cancers.

Specifications

• Antigen: TMEM184C
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TMEM184C
• Gene Accession No.: Q9NVA4
• Gene Alias: 8430433H16Rik; AI645453; AL033298; BC004056; DNA sequence AY228474; PRO1355; TMEM184C; Tmem34; Transmembrane protein 184C; transmembrane protein 34
• Gene Symbols: TMEM184C
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human TMEM184C. Recombinant protein control fragment (Product #RP-101430).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55751
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG