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Invitrogen™ TMEM189 Polyclonal Antibody
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Catalog No. PIPA597031
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100 μL
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PIPA597031 100 μL
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Catalog No. PIPA597031 Supplier Invitrogen™ Supplier No. PA597031
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Description

Rabbit Polyclonal Antibody

Positive Samples: MCF7; Cellular Location: Endoplasmic reticulum membrane, Multi-pass membrane protein Immunogen sequence: FVFCLIIFGT FTNQIHKWSH TYFGLPRWVT LLQDWHVILP RKHHRIHHVS PHETYFCITT GWLNYPLEKI GFWRRLEDLI QGLTGEKPRA DDMKWAQKIK.

Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM189
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 2.41 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene TMEM189
Gene Accession No. A5PLL7
Gene Alias KUA; TMEM189; transmembrane protein 189
Gene Symbols TMEM189
Host Species Rabbit
Immunogen Synthetic peptide.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 387521
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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