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TMEM24 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734938 Shop All Proteintech Group Inc Products
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50-173-4938 150 μL
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Catalog No. 50-173-4938 Supplier Proteintech Group Inc Supplier No. 255071AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody detects TMEM24 protein with MW 70-100 kDa.

DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive genes. Involved in both enhancer blocking and epigenetic remodeling at chromatin boundary via its interaction with CTCF. Acts as a suppressor of STAT3 activity by suppressing the LIF-induced STAT3 transcriptional activity. Also acts as a transcription activator via its interaction with ZNF143 by participating in efficient U6 RNA polymerase III transcription.

Specifications

Antigen TMEM24
Applications Western Blot
Classification Polyclonal
Concentration 0.29 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene C2CD2L
Gene Accession No. O14523
Gene Alias C2CD2 like, C2CD2L, DLNB23, KIAA0285, TMEM24, Transmembrane protein 24
Gene Symbols C2CD2L
Host Species Rabbit
Immunogen TMEM24 Fusion Protein Ag21913
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9854
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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