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Invitrogen™ TMEM245 Polyclonal Antibody
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Catalog No. PIPA554916
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PIPA554916 100 μL
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Catalog No. PIPA554916 Supplier Invitrogen™ Supplier No. PA554916
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: AELPGQVISM AASTLANLAI SITGYESSSE DQPSTQPAEA VDRGESAPTL STSPSPSSPS PTSPSPTLGR RRPEIGTFLR KKK Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 79%.

C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein that is widely expressed and exists as four alternatively spliced isoforms. The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM245
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TMEM245
Gene Accession No. Q9H330
Gene Alias C9orf5; CG2; CG-2; protein CG-2; TMEM245; Transmembrane protein 245; transmembrane protein C9orf5
Gene Symbols TMEM245
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TMEM245. Recombinant protein control fragment (Product #RP-92899).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23731
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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