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Invitrogen™ TMEM259 Polyclonal Antibody
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Catalog No. PIPA531230
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100 μL
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PIPA531230 100 μL
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Catalog No. PIPA531230 Supplier Invitrogen™ Supplier No. PA531230
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: K562, THP-1, HL-60. Predicted reactivity: Mouse (84%), Rat (84%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM259
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene TMEM259
Gene Accession No. Q4ZIN3
Gene Alias AC087114.7gm2; ASBABP1; aspecific BCL2 ARE-binding protein 1; C19orf6; C20H19orf6; im:7154960; MBRL; MEMBRALIN; mFLJ00277; ORF61; R32184_3; RGD1311136; TMEM259; Transmembrane protein 259
Gene Symbols TMEM259
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human Membralin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91304
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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