Invitrogen™ TMEM43 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA598199

Catalog No. PIPA598199

Description

TMEM43 Polyclonal Antibody for Western Blot, IHC (P), ELISA

This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.

Specifications

• Antigen: TMEM43
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM43
• Gene Alias: 1200015A22Rik; ARVC5; ARVD5; EDMD7; LUMA; Protein LUMA; Tmem43; Transmembrane protein 43; UNQ2564/PRO6244
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 74122, 79188
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 4 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q9BTV4, Q9DBS1
• Gene Symbols: TMEM43
• Immunogen: Recombinant Human Transmembrane protein 43 protein (178-312AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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