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Invitrogen™ TMEM59 Polyclonal Antibody
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Catalog No. PIPA598200
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100 μg
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PIPA598200 100 μg
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Catalog No. PIPA598200 Supplier Invitrogen™ Supplier No. PA598200
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Description

Rabbit Polyclonal Antibody

TMEM59 Polyclonal Antibody for Western Blot, ICC/IF, ELISA

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM59
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene TMEM59
Gene Accession No. Q9BXS4
Gene Alias 1110001M20Rik; 3110046P06Rik; AI256529; C1orf8; D4Ertd20e; DCF1; dendritic cell factor 1; HSPC001; Liver membrane-bound protein; MTDCF1; ORF18; PRO195; RGD1310313; RP4-758J24.2; Tdcf1; Thymic dendritic cell-derived factor 1; TMEM59; Transmembrane protein 59; UNQ169; UNQ169/PRO195
Gene Symbols TMEM59
Host Species Rabbit
Immunogen Recombinant Human Transmembrane protein 59 protein (59-201AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9528
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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