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TMEM59 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981548
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50-198-1548 100 μL
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Catalog No. 50-198-1548 Supplier Bioss Supplier No. BS11647R
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Description

Rabbit Polyclonal Antibody

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.

Specifications

Antigen TMEM59
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TMEM59
Gene Accession No. Q9BXS4
Gene Alias 1110001M20Rik; 3110046P06Rik; AI256529; C1orf8; D4Ertd20e; DCF1; dendritic cell factor 1; HSPC001; Liver membrane-bound protein; MTDCF1; ORF18; PRO195; RGD1310313; RP4-758J24.2; Tdcf1; Thymic dendritic cell-derived factor 1; Tmem59; Transmembrane protein 59; UNQ169; UNQ169/PRO195
Gene Symbols TMEM59
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TMEM59.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9528
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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