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TMEM59 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 241341AP150UL

Encompass_Preferred

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Catalog No. 50-173-4244


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Description

Description

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.
Specifications

Specifications

TMEM59
Polyclonal
Unconjugated
TMEM59
C1orf8, HSPC001, Liver membrane bound protein, TMEM59, transmembrane protein 59, UNQ169/PRO195
Rabbit
Antigen Affinity Chromatography
RUO
9528
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.15 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q9BXS4
TMEM59
TMEM59 Fusion Protein Ag21150
150 μL
Primary
Human
Antibody
IgG
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