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TMEM59 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501734244 Shop All Proteintech Group Inc Products
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50-173-4244 150 μL
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Catalog No. 50-173-4244 Supplier Proteintech Group Inc Supplier No. 241341AP150UL
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Description

Rabbit Polyclonal Antibody

Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.

Specifications

Antigen TMEM59
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TMEM59
Gene Accession No. Q9BXS4
Gene Alias C1orf8, HSPC001, Liver membrane bound protein, TMEM59, transmembrane protein 59, UNQ169/PRO195
Gene Symbols TMEM59
Host Species Rabbit
Immunogen TMEM59 Fusion Protein Ag21150
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9528
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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