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Invitrogen™ TMEM66 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA524237

Catalog No. PIPA524237


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Description

Description

TMEM66 Polyclonal Antibody for Western Blot, Flow

Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TMEM66
Polyclonal
Unconjugated
SARAF
1810045K07Rik; arrestin-E; FOAP-7; HBV XAg-transactivated protein 3; HBV X-transactivated gene 3 protein; HSPC035; NPD003; Protein FOAP-7; PSEC0019; Saraf; SARAF long isoform; SARAF short isoform; SOCE-associated regulatory factor; store-operated calcium entry associated regulatory factor; store-operated calcium entry-associated regulatory factor; testicular secretory protein Li 59; TMEM66; Transmembrane protein 66; UNQ1967/PRO4499; XTP3
Rabbit
Antigen Affinity Chromatography, Protein A
RUO
51669, 67887
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Flow Cytometry, Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.4
Q8R3Q0, Q96BY9
SARAF
KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human TMEM66.
400 μL
Primary
Human, Mouse
Antibody
IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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