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Invitrogen™ TMEM66 Polyclonal Antibody
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Catalog No. PIPA524237
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400 μL
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PIPA524237 400 μL
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Catalog No. PIPA524237 Supplier Invitrogen™ Supplier No. PA524237
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Description

Rabbit Polyclonal Antibody

TMEM66 Polyclonal Antibody for Western Blot, Flow

Saraf encodes a protein that is a negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the de-oligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM66
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene SARAF
Gene Accession No. Q8R3Q0, Q96BY9
Gene Alias 1810045K07Rik; arrestin-E; FOAP-7; HBV XAg-transactivated protein 3; HBV X-transactivated gene 3 protein; HSPC035; NPD003; Protein FOAP-7; PSEC0019; Saraf; SARAF long isoform; SARAF short isoform; SOCE-associated regulatory factor; store-operated calcium entry associated regulatory factor; store-operated calcium entry-associated regulatory factor; testicular secretory protein Li 59; TMEM66; Transmembrane protein 66; UNQ1967/PRO4499; XTP3
Gene Symbols SARAF
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human TMEM66.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51669, 67887
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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