Invitrogen™ TMEM70 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554717

Catalog No. PIPA554717

Description

Immunogen sequence: KGYVIRLYHE ATTDTYKAIT YNAMLAETST VFHQNDVKIP DAKHVFTTFY AKTKSLLVNP VLFPNREDYI HLMGYDKEEF ILYMEETSEE KRHKDDK Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Specifications

• Antigen: TMEM70
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM70
• Gene Alias: 1110020A09Rik; 2210416J16Rik; MC5DN2; RGD1566224; TMEM70; transmembrane protein 70; transmembrane protein 70, mitochondrial
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54968
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BUB7
• Gene Symbols: TMEM70
• Immunogen: Recombinant protein corresponding to Human TMEM70. Recombinant protein control fragment (Product #RP-91012).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG