Invitrogen™ TMEM70 Polyclonal Antibody

Catalog No.	Quantity
PIPA554717	100 μL

Catalog No. PIPA554717 Supplier Invitrogen™ Supplier No. PA554717

Description

Rabbit Polyclonal Antibody

Immunogen sequence: KGYVIRLYHE ATTDTYKAIT YNAMLAETST VFHQNDVKIP DAKHVFTTFY AKTKSLLVNP VLFPNREDYI HLMGYDKEEF ILYMEETSEE KRHKDDK Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.

TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.

Specifications

• Antigen: TMEM70
• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.05 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: TMEM70
• Gene Accession No.: Q9BUB7
• Gene Alias: 1110020A09Rik; 2210416J16Rik; MC5DN2; RGD1566224; TMEM70; transmembrane protein 70; transmembrane protein 70, mitochondrial
• Gene Symbols: TMEM70
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human TMEM70. Recombinant protein control fragment (Product #RP-91012).
• Purification Method: Antigen Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 54968
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG