Invitrogen™ TMEM88 Polyclonal Antibody

Catalog No.	Quantity
PIPA5144031	100 μg

Catalog No. PIPA5144031 Supplier Invitrogen™ Supplier No. PA5144031

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human MCF-7 whole cell. ICC/IF: U20S cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Transmembrane protein 88 (TMEM88) is a two-transmembrane-type protein whose C-terminal tail has been shown to bind the PDZ domain of Dishevelled (Dvl), one of the key components in Wnt signaling pathways. TMEM88 attentuated the Wnt/beta-catenin signaling induced by Wnt-1 ligand in a dose-dependent manner and knockdown of TMEM88 by RNAi increased Wnt activity, suggesting that TMEM88 plays a role in regulating Wnt signaling in a context-dependent manner.

Specifications

• Antigen: TMEM88
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: TMEM88
• Gene Accession No.: Q6PEY1
• Gene Alias: 2600017H02Rik; RGD1561781; TMEM88; TMEM88A; Transmembrane protein 88
• Gene Symbols: TMEM88
• Host Species: Rabbit
• Immunogen: A synthetic peptide corresponding to a sequence of human TMEM88 (RALYRRRRAPQPRQIRA).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 92162
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG