Invitrogen™ TMPRSS11F Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555461

Catalog No. PIPA555461

Description

Immunogen sequence: NKDPTQWIAT FGATITPPAV KRNVRKIILH ENYHRETNEN DIALVQLSTG VEFSNIVQRV CLPDSSIKLP PKTSVFVTGF GSIVDDGPIQ NTLRQARVET ISTDVCNRKD VYDG Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

TMPRSS11F is a type-II transmembrane protease, similar to hepsin (TMPRSS1). TMPRSS11F is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase-1, 2 and 3. TMPRSS11F has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin-like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but its role in TMPRSS11F is unclear. The cleavage of the Arg206-Ile207 bond is thought to liberate the catalytic domain.

Specifications

• Antigen: TMPRSS11F
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMPRSS11F
• Gene Alias: 4631408C20; 4732406D01Rik; airway trypsin-like protease 4; HATL4; TMPRSS11F; Transmembrane protease serine 11F; transmembrane protease, serine 11f
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 389208
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q6ZWK6
• Gene Symbols: TMPRSS11F
• Immunogen: Recombinant protein corresponding to Human TMPRSS11F. Recombinant protein control fragment (Product #RP-90611).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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