Invitrogen™ TMPRSS2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116054

Catalog No. PIPA5116054

Description

Antibody detects endogenous levels of total TMPRSS2.

TMPRSS2 is a protein that belongs to the serine protease family. The protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. Its gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage.

Specifications

• Antigen: TMPRSS2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMPRSS2
• Gene Alias: D16Ertd61e; EC 3.4.219; epitheliasin; FLJ41954; MGC6821; Plasmic transmembrane protein X; PP9284; PRSS10; Serine protease 10; Tmprss2; TMPS2; Transmembrane protease serine 2; Transmembrane protease serine 2 catalytic chain; Transmembrane protease serine 2 non-catalytic chain; transmembrane protease, serine 2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 50528, 7113
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O15393, Q9JIQ8
• Gene Symbols: TMPRSS2
• Immunogen: A synthesized peptide derived from human TMPRSS2(Accession O15393), corresponding to amino acid residues L315-C365.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov