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TMPRSS3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549817

Catalog No. PA549817


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Description

Description

The antibody detects endogenous levels of total TMPRSS3 protein.

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintece of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described.
Specifications

Specifications

TMPRSS3
Polyclonal
Unconjugated
TMPRSS3
Liquid
TMPRSS3
Synthesized peptide derived from C-terminal of human TMPRSS3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P57727, Q8K1T0
ECHOS1, TADG12
Rabbit
IgG
100 μL
-20°C
Primary
140765, 64699
Documents
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