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Invitrogen™ TMPRSS6 Polyclonal Antibody
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Catalog No. PIPA543989
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100 μL
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PIPA543989 100 μL
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Catalog No. PIPA543989 Supplier Invitrogen™ Supplier No. PA543989
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Description

Rabbit Polyclonal Antibody

Peptide sequence: LLWYFLGYKA EVMVSQVYSG SLRVLNRHFS QDLTRRESSA FRSETAKAQK Sequence homology: Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%.

TMPRSS6 is a serine protease which hydrolyzes a range of proteins including type I collagen, fibronectin and fibrinogen. TMPRSS6 can also activate urokinase-type plasminogen activator with low efficiency. TMPRSS6 may play a specialized role in matrix remodeling processes in liver. TMPRSS6 is required to sense iron deficiency. Overexpression of TMPRSS6 suppresses activation of the HAMP promoter. The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMPRSS6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TMPRSS6
Gene Accession No. Q8IU80
Gene Alias 1300008A22Rik; IRIDA; matriptase 2; matriptase-2; membrane-bound mosaic serine proteinase matriptase-2; Tmprss6; Transmembrane protease serine 6; transmembrane protease, serine 6; transmembrane serine protease 6; type II transmembrane serine protease 6; UNQ354/PRO618
Gene Symbols TMPRSS6
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human TMPRSS6 (aa 71-120).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 164656
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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