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Invitrogen™ TNF beta Monoclonal Antibody (LTX-22), eBioscience™
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Catalog No. 5017715
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100 μg
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Catalog No. Quantity
50-177-15 100 μg
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Catalog No. 50-177-15 Supplier Invitrogen™ Supplier No. BMS1046
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Mouse Monoclonal Antibody

Description: BMS1046 (LTX-22) is reportded for ELISA and ICH applications. Applications Tested: ELISA, Immunohistochemistry (Frozen). Source: Plant expressed 164 amino acids (Cys32-Thr194) with 16 amino acid Histidine tag. accession NP_002000. Bioactivity: The ED50 of this protein, as measured by proliferation assay of 4MBr5 monkey epthelial cells, is less than or equal to 4 ng/mL. This corresponds to a specific activity of greater than or equal to 2.5 x 10e5 Units/mg. Endotoxin: Less than 0.005 ng/ug (0.05 EU/ug) as measured by turbidity assay. Purity: Greater than or equal to 95% as determined by SDS-PAGE. Molecular Weight: 21.2 kDa but with glycosylation the apparent molecular weights are 26 and 28 kDa.

TNF beta, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
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Specifications

Antigen TNF beta
Applications ELISA, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone LTX-22
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.2-7.4
Gene LTA
Gene Accession No. P01374
Gene Alias DAMA-25N12.13; hlb382; hypothetical protein; LT; LT[a]; LT-[a]; LTA; LTalpha; LT-alpha; Ltx; lymphotoxin A; lymphotoxin alpha; lymphotoxin alpha (TNF superfamily, member 1); lymphotoxin-alpha; lymphotoxin-alpha; lymphotoxin alpha; TNF b; TNF beta; TNF superfamily, member 1; TNF β; Tnfb; TNFbeta; TNF-beta; TNF-N; Tnfsf1; Tnfsf1b; TNFβ; TNLG1E; tumor necrosis factor beta; tumor necrosis factor ligand 1E; tumor necrosis factor ligand superfamily member 1
Gene Symbols LTA
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4049
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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