TNF Mouse anti-Human, PE, Clone: MAB11, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 559321

Catalog No. BDB559321

Description

The MAb11 antibody reacts with human tumor necrosis factor (TNF, formerly known as TNF-α) protein. TNF is an efficient paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN-γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The use of the MAb11 antibody has been reported to cross-react with TNF of rhesus monkey. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Intracellular Staining

Specifications

• Antigen: TNF
• Classification: Monoclonal
• Conjugate: PE
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: MAB11
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Recombinant Human TNF
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Human
• Isotype: IgG1 κ

For Research Use Only.