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Invitrogen™ TNFAIP8 Monoclonal Antibody (OTI1H9)
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Catalog No. PIMA527345
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100 μL
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PIMA527345 100 μL
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Catalog No. PIMA527345 Supplier Invitrogen™ Supplier No. MA527345
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Description

Mouse Monoclonal Antibody

TNFAIP8 Monoclonal Antibody for Western Blot, IHC (P)

TNFalpha-IP 8 (tumor necrosis factor, alpha-induced protein 8), also known as NFkappa B-inducible DED-containing protein (NDED), SCC-S2 or TNF-induced protein GG2-1, is a 198 amino acid cytoplasmic protein induced by NFkappa B and TNF. The induction of TNFalpha-IP 8 by TNF is dependent on the activation of NFkappa B. TNFalpha-IP 8 negatively mediates apoptosis and may also play a role in tumor progression. TNFalpha-IP 8 specifically inhibits caspase-8 activity, which results in the inhibition of BID cleavage and caspase-3 activation during TNF-mediated apoptosis. TNFalpha-IP 8 is expressed at high levels in thymus, bone marrow, lymph node, spleen, thyroid, placenta and various tumor tissues, as well as fetal lung, liver and kidney. TNFalpha-IP 8 is present as three isoforms produced by alternative splicing.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFAIP8
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI1H9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Tnfaip8
Gene Accession No. O95379
Gene Alias AA987150; E130304C20Rik; ENSMUSG00000073567; GG2-1; Gm10539; head and neck tumor and metastasis-related protein; MDC3.13; MDC-3.13; Nded; NF-kappa-B-inducible DED-containing protein; SCC S2; SCCS2; SCC-S2; Ssc-2; TNF alpha induced protein 8; TNF alpha-induced protein 8; Tnfaip8; TNFalpha IP8; TNFalpha-IP 8; TNFalphaIP8; TNF-induced protein; TNF-induced protein GG2-1; Tumor necrosis factor alpha-induced protein 8; tumor necrosis factor, alpha induced protein 8; tumor necrosis factor, alpha-induced protein 8
Gene Symbols Tnfaip8
Host Species Mouse
Immunogen Full length human recombinant protein of TNFAIP8 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25816
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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