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Invitrogen™ TNFAIP8L1 Polyclonal Antibody
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Catalog No. PIPA575717
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PIPA575717 100 μL
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Catalog No. PIPA575717 Supplier Invitrogen™ Supplier No. PA575717
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFAIP8L1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene TNFAIP8L1
Gene Accession No. Q8WVP5
Gene Alias 2600017J23Rik; Oxidative stress regulated gene-beta; oxidative stress-regulated gene-beta; Oxy-beta; TIPE1; TNF alpha induced protein 8 like 1; TNF alpha-induced protein 8-like protein 1; Tnfaip8l1; TNFAIP8-like protein 1; Tumor necrosis factor alpha-induced protein 8-like protein 1; tumor necrosis factor, alpha induced protein 8 like 1; tumor necrosis factor, alpha-induced protein 8-like 1; tumor necrosis factor, alpha-induced protein 8-like protein 1
Gene Symbols TNFAIP8L1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues in Human TNFAIP8L1.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126282
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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