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Invitrogen™ TNFAIP8L1 Polyclonal Antibody
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Catalog No. PIPA5103341
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100 μL
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PIPA5103341 100 μL
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Catalog No. PIPA5103341 Supplier Invitrogen™ Supplier No. PA5103341
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TNFAIP8L1.

Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFAIP8L1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TNFAIP8L1
Gene Accession No. Q8K288, Q8WVP5
Gene Alias 2600017J23Rik; Oxidative stress regulated gene-beta; oxidative stress-regulated gene-beta; Oxy-beta; TIPE1; TNF alpha induced protein 8 like 1; TNF alpha-induced protein 8-like protein 1; Tnfaip8l1; TNFAIP8-like protein 1; Tumor necrosis factor alpha-induced protein 8-like protein 1; tumor necrosis factor, alpha induced protein 8 like 1; tumor necrosis factor, alpha-induced protein 8-like 1; tumor necrosis factor, alpha-induced protein 8-like protein 1
Gene Symbols TNFAIP8L1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TNFAIP8L1(Accession Q8WVP5), corresponding to amino acid residues V29-L79.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 126282, 301131, 66443
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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