Invitrogen™ TNFAIP8L1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103341

Catalog No. PIPA5103341

Description

Antibody detects endogenous levels of total TNFAIP8L1.

Tumor necrosis factor, α-induced protein 8-like 1, also known as TNFα-IP 8L1, is a 186 amino acid protein belonging to the TNFα-IP 8 family. Members of the TNFα-IP 8 family are induced by nuclear factor-κB 9 (NFκB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NFκB activation. TNFα-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.

Specifications

• Antigen: TNFAIP8L1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TNFAIP8L1
• Gene Alias: 2600017J23Rik; Oxidative stress regulated gene-beta; oxidative stress-regulated gene-beta; Oxy-beta; TIPE1; TNF alpha induced protein 8 like 1; TNF alpha-induced protein 8-like protein 1; Tnfaip8l1; TNFAIP8-like protein 1; Tumor necrosis factor alpha-induced protein 8-like protein 1; tumor necrosis factor, alpha induced protein 8 like 1; tumor necrosis factor, alpha-induced protein 8-like 1; tumor necrosis factor, alpha-induced protein 8-like protein 1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 126282, 301131, 66443
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q8K288, Q8WVP5
• Gene Symbols: TNFAIP8L1
• Immunogen: A synthesized peptide derived from human TNFAIP8L1(Accession Q8WVP5), corresponding to amino acid residues V29-L79.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov