Invitrogen™ TNFAIP8L2 Recombinant Rabbit Monoclonal Antibody (19H35L22)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 703165

Catalog No. 70-316-5

Description

This antibody is predicted to react with Human, Mouse, Monkey, Pig, Horse, Cat. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

TNFAIP8L2 - Tumor necrosis factor alpha-induced protein 8-like protein 2 (also known as TIPE2) acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. It is a negative regulator of Toll-like receptor and T-cell receptor functions. TIPE2 prevents hyperresponsiveness of the immune system and maintains immune homeostasis. It inhibits JUN/AP1 and NF-kappa-B activation. TIPE2 also promotes Fas-induced apoptosis.

Specifications

• Antigen: TNFAIP8L2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q6P589, Q9D8Y7
• Gene Symbols: Tnfaip8l2
• Immunogen: Protein corresponding to human TNFAIP8L2 [aa45-aa184].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunocytochemistry
• Clone: 19H35L22
• Conjugate: Unconjugated
• Gene: Tnfaip8l2
• Gene Alias: 1810019A08Rik; AW610835; inflammation factor 20; inflammation factor protein 20; RGD1310519; TIPE2; TNF alpha induced protein 8 like 2; TNF alpha-induced protein 8-like protein 2; Tnfaip8l2; TNFAIP8-like protein 2; TP8L2; Tumor necrosis factor alpha-induced protein 8-like protein 2; tumor necrosis factor, alpha induced protein 8 like 2; tumor necrosis factor, alpha-induced protein 8-like 2; tumor necrosis factor, alpha-induced protein 8-like protein 2
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 69769, 79626
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

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