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Invitrogen™ TNFR2 Polyclonal Antibody
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Catalog No. PIPA587429
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100 μL
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PIPA587429 100 μL
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Catalog No. PIPA587429 Supplier Invitrogen™ Supplier No. PA587429
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPYAPEPGST CRLREYYDQT AQMCCSKCSP GQHAKVFCTK TSDTVCDSCE DSTYTQLWNW VPECLSCGSR CSSDQVETQA CTREQNRICT CRPGWYCALS KQEGCRLCAP LRKCRPGFGV ARPGTETSDV VCKPCAPGTF SNTTSSTDIC RPHQICNVVA IPGNASMDAV CTSTSPTRSM APGAVHLPQP VSTRSQHTQP TPEPSTAPST SFLLPMGPSP P; Positive Samples: THP-1; Cellular Location: Cell membrane, Single-pass type I membrane protein.

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFR2
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Tnfrsf1b
Gene Accession No. P20333
Gene Alias CD120b; Etanercept; p75; p75 TNF receptor; p75 TNFR; p75TNFR; p80 TNF-alpha receptor; sCD120b; soluble CD120b; soluble TNFR1B variant 1; soluble TNFR2; sTNF R2; sTNFR 2; sTNFR2; TBP-2; TBPII; TNF receptor beta chain; TNF receptor superfamily member 1B; TNF-alphaR2; TNFalpha-R2; TNFBR; TNFR; TNFR II; Tnfr-1; TNFR1B; TNFR2; TNF-R2; Tnfr-2; TNF-R75; TNFR80; TNFRII; TNF-RII; TNF-R-II; TNFR-II; TNFRSF1B; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; Tumor necrosis factor receptor; tumor necrosis factor receptor 2; Tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1b, membrane form; tumor necrosis factor receptor superfamily, member 1B; tumor necrosis factor receptor type II; Tumor necrosis factor-binding protein 2
Gene Symbols Tnfrsf1b
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human TNFR2/TNFR2/TNFRSF1B (NP_0010571).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7133
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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