Invitrogen™ TNFRSF11B Monoclonal Antibody (5A11)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515726

Catalog No. PIMA515726

Description

MA5-15726 targets TNFRSF11B in indirect ELISA, IHC and WB applications and shows reactivity with Human samples. The MA5-15726 immunogen is purified recombinant fragment of human TNFRSF11B expressed in E. Coli. MA5-15726 detects TNFRSF11B which has a predicted molecular weight of approximately 60kDa.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Specifications

• Antigen: TNFRSF11B
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.03% sodium azide
• Gene Accession No.: O00300
• Gene Symbols: TNFRSF11B
• Immunogen: Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 4982
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Clone: 5A11
• Conjugate: Unconjugated
• Gene: TNFRSF11B
• Gene Alias: LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1