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Invitrogen™ TNFRSF11B Monoclonal Antibody (5G2)
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Catalog No. PIMA515715
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100 μL
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PIMA515715 100 μL
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Catalog No. PIMA515715 Supplier Invitrogen™ Supplier No. MA515715
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Mouse Monoclonal Antibody

MA5-15715 targets TNFRSF11B in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15715 immunogen is purified recombinant fragment of human TNFRSF11B expressed in E. Coli. MA5-15715 detects TNFRSF11B which has a predicted molecular weight of approximately 60kDa.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFRSF11B
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 5G2
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Ascites with 0.03% sodium azide
Gene TNFRSF11B
Gene Accession No. O00300
Gene Alias LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Gene Symbols TNFRSF11B
Host Species Mouse
Immunogen Purified recombinant fragment of human TNFRSF11B expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4982
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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