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Invitrogen™ TNFRSF11B Polyclonal Antibody
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Catalog No. PIPA589117
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100 μL
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PIPA589117 100 μL
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Catalog No. PIPA589117 Supplier Invitrogen™ Supplier No. PA589117
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ETFPPKYLHY DEETSHQLLC DKCPPGTYLK QHCTAKWKTV CAPCPDHYYT DSWHTSDECL YCSPVCKELQ YVKQECNRTH NRVCECKEGR YLEIEFCLKH RSCPPGFGVV QAGTPERNTV CKRCPDGFFS NETSSKAPCR KHTNCSVFGL LLTQKGNATH DNICSGNSES TQKCGIDVTL CEEAFFRFAV PTKFTPNWLS VLVDNLPGTK VNAESVERIK RQHSSQEQTF QLLKLWKHQN KDQDIVKKII QDIDLCENS; Positive Samples: 293T, Rat liver.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFRSF11B
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.97 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene TNFRSF11B
Gene Accession No. O00300, O08712, O08727
Gene Alias LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B; MGC29565; OCIF; Opg; osteoclastogenesis inhibitory factor; Osteoprotegerin; PDB5; soluble OPG; soluble Osteoprotegerin; sOPG; TNF receptor superfamily member 11b; TNFRSF11B; TR1; tumor necrosis factor receptor superfamily member 11B; tumor necrosis factor receptor superfamily, member 11b; tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
Gene Symbols TNFRSF11B
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 22-280 of human TNFRSF11B (NP_0025373).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18383, 25341, 4982
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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