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TNFRSF14/HVEM Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984745
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50-198-4745 100 μL
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Catalog No. 50-198-4745 Supplier Bioss Supplier No. BS2457R
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Description

Rabbit Polyclonal Antibody

TNFRSF14 is a member of the TNF-receptor superfamily. TNFRSF14 was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 has been shown to be part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Activation of the signal transduction pathway involving TNFRSF14 in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these TNFRSF14 variants have not been determined.

Specifications

Antigen TNFRSF14/HVEM
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TNFRSF14
Gene Accession No. Q92956
Gene Alias Atar; CD270; CD40-like protein; herpes virus entry mediator; Herpes virus entry mediator A; Herpesvirus entry mediator A; HGNC:11912; HVEA; HVEM; LIGHTR; RP3-395M20.6; sCD2710; TNF receptor superfamily member 14; Tnfrs14; Tnfrsf14; TR2; tumo; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; UNQ329/PRO509
Gene Symbols TNFRSF14
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TNFRSF14 .
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8764
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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