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  6. Invitrogen™ TNFRSF14 (HVEM) Recombinant Rabbit Monoclonal Antibody (BLR062G)

Invitrogen™ TNFRSF14 (HVEM) Recombinant Rabbit Monoclonal Antibody (BLR062G)
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Catalog No. PIMA544317
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100 μL
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PIMA544317 100 μL
PIMA544318 10 μL
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Catalog No. PIMA544317 Supplier Invitrogen™ Supplier No. MA544317
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Description

Rabbit Recombinant Monoclonal Antibody

Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE cell sections.

TNFRSF14 is a member of the TNF-receptor superfamily. TNFRSF14 was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to TNFRSF14 has been shown to be part of the viral entry mechanism. The cytoplasmic region of TNFRSF14 was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. Activation of the signal transduction pathway involving TNFRSF14 in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these TNFRSF14 variants have not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNFRSF14 (HVEM)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone BLR062G
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation BBS with 0.09% sodium azide; pH 8.2
Gene TNFRSF14
Gene Accession No. Q92956
Gene Alias Atar; CD270; CD40-like protein; herpes virus entry mediator; herpes virus entry mediator A; Herpesvirus entry mediator A; HGNC:11912; HVEA; Hvem; LIGHTR; RP3-395M20.6; sCD2710; TNF receptor superfamily member 14; Tnfrs14; TNFRSF14; TR2; tumo; Tumor necrosis factor receptor superfamily member 14; tumor necrosis factor receptor superfamily, member 14; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); Tumor necrosis factor receptor-like 2; tumor necrosis factor receptor-like gene2; UNQ329/PRO509
Gene Symbols TNFRSF14
Host Species Rabbit
Immunogen Recombinant protein representing the extracellular domain of human TNF receptor superfamily member 14, transcript variant 1 (Herpesvirus entry mediator A, HVEM) (residues 39-200).
Purification Method Purified
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8764
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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