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TNFRSF4 Rabbit anti-Human, Clone:RM313, Abnova™

Catalog No. 89333294 Shop All Abnova Corporation Products
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89-333-294 100 μL
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Catalog No. 89-333-294 Supplier Abnova Corporation Supplier No. MAB16938
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Rabbit monoclonal antibody raised against huamn TNFRSF4.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq]

Specifications

Antigen TNFRSF4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone RM313
Conjugate Unconjugated
Description tumor necrosis factor receptor superfamily, member 4
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-500)
Western Blot (1:1000-2000)
The optimal working dilution should be determined by the end user.
Formulation In PBS (50% glycerol, 1% BSA, 0.09% sodium azide)
Gene TNFRSF4
Gene Alias ACT35, CD134, OX40, TXGP1L
Host Species Rabbit
Immunogen A peptide corresponding to C-terminus of human TNFRSF4.
Quantity 100 μL
Gene ID (Entrez) 7293
Test Specificity This antibody reacts to human TNFRSF4 (CD134).
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Liquid
Isotype IgG
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