TNFRSF8 Mouse anti-Human, Clone: Ki-1/779, Abnova™

Mouse monoclonal antibody raised against full length recombinant human TNFRSF8.

Supplier:  Abnova Corporation MAB13464

Catalog No. 89-935-034

Description

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

• Antigen: TNFRSF8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (0.5-1 ug/10⁶ cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: CD30/D1S166E/KI-1
• Host Species: Mouse
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 943
• Content And Storage: Store at -20 to -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Clone: Ki-1/779
• Description: Mouse monoclonal antibody raised against full length recombinant human TNFRSF8.
• Formulation: In 10mM PBS.
• Gene Symbols: TNFRSF8
• Immunogen: Recombinant protein corresponding to full length human TNFRSF8.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid