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TNFRSF8 Mouse anti-Human, Clone: SPM121, Abnova™

Catalog No. 89935036 Shop All Abnova Corporation Products
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500 μL
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Catalog No. Quantity
89-935-036 500 μL
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Catalog No. 89-935-036 Supplier Abnova Corporation Supplier No. MAB13015
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Description

Mouse monoclonal antibody raised against native human TNFRSF8.

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]

Specifications

Antigen TNFRSF8
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone SPM121
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native human TNFRSF8.
Dilution Flow Cytometry (0.5-1 ug/million cells in 0.1 mL) Immunofluorescence (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In tissue culture supernatant (0.05% sodium azide).
Gene Alias CD30/D1S166E/KI-1
Gene Symbols TNFRSF8
Host Species Mouse
Immunogen CO cell line established from a patient with Hodgkin's disease of T-cell lineage.
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 943
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1 κ
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