TNFSF12 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-8047	150 μL

Catalog No. 50-172-8047 Supplier Proteintech Group Inc Supplier No. 125371AP150UL

Description

Rabbit Polyclonal Antibody

TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.

Specifications

• Antigen: TNFSF12
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.29 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: TNFSF12
• Gene Accession No.: O43508
• Gene Alias: APO3 ligand, APO3L, DR3LG, TNFSF12, TWEAK
• Gene Symbols: TNFSF12
• Host Species: Rabbit
• Immunogen: TNFSF12 Fusion Protein Ag3242
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8742
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG