TNFSF4 Monoclonal Antibody (OTI5D8), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-1221	100 μL

Catalog No. 50-168-1221 Supplier OriGene Supplier No. TA806677

Description

Mouse Monoclonal Antibody

The tumor necrosis factor superfamily member TNFSF4 is a type II membrane bound, non-covalently linked homotrimeric protein. It is expressed on antigen presenting cells, such as dendritic cells and activated B-cells, and also on other cells such as vascular endothelial cells, mast cells, and natural killer cells. TNFSF4 signals specifically through the TNFRSF4 receptor, is expressed predomitly on CD4+T cells but also on certain activated CD8+T cells. TNFRSF4/TNFSF4 functions as a costimulatory signal, which is required for a productive interaction between antigen presenting cells and their target T-cells. It enhances cell proliferation and survival, and increases expression of RANTES, IL-2, IL-3, and IFNgamma. TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.

Specifications

• Antigen: TNFSF4
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI5D8
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: TNFSF4
• Gene Accession No.: P23510
• Gene Alias: CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1
• Gene Symbols: TNFSF4
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human TNFSF4 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7292
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1