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Invitrogen™ TNIK Recombinant Rabbit Monoclonal Antibody (HL1751)
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Catalog No. PIMA547168
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100 μL
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PIMA547168 100 μL
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Catalog No. PIMA547168 Supplier Invitrogen™ Supplier No. MA547168
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Description

Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

TNIK or TRAF2 and NCK interacting kinase is characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function. TNIK is mainly expression in brain, heart, and spleen and it is a specific effector of RAP2 which regulate actin cytoskeleton. TNIK is autophosphorylated in a manner dependent upon lys54 in the ATP-binding pocket of its kinase domain and plays a main role in cytoskeleton regulation. TNIK has also been shown to phosphorylate gelsolin, the principal intracellular and extracellular actin-severing protein, in vitro. This and evidence from mutational studies suggest that TNIK functions in the regulation of the cytoskeleton.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNIK
Applications Western Blot
Classification Recombinant Monoclonal
Clone HL1751
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene TNIK
Gene Accession No. Q9UKE5
Gene Alias 1500031A17Rik; 4831440I19Rik; AI451411; C530008O15Rik; C630040K21Rik; KIAA0551; RGD1561817; Tnik; TRAF2 and NCK interacting kinase; TRAF2 and NCK-interacting protein kinase
Gene Symbols TNIK
Host Species Rabbit
Immunogen Synthetic peptide of human TNIK.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23043
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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