Invitrogen™ TNK1 Monoclonal Antibody (1B5G3;3F11H6)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA515413

Catalog No. PIMA515413

Description

MA5-15413 targets TNK1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15413 immunogen is purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli. .

TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.

Specifications

• Antigen: TNK1
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: ascites with 0.03% sodium azide
• Gene Accession No.: Q13470
• Gene Symbols: TNK1
• Immunogen: Purified recombinant fragment of TNK1 (aa451-560) expressed in E. Coli.
• Regulatory Status: RUO
• Gene ID (Entrez): 8711
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: 1B5G3;3F11H6
• Conjugate: Unconjugated
• Gene: TNK1
• Gene Alias: CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1