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Invitrogen™ TNK1 Polyclonal Antibody
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Catalog No. PIPA5110771
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PIPA5110771 100 μL
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Catalog No. PIPA5110771 Supplier Invitrogen™ Supplier No. PA5110771
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PSEACCVRDV TEPGALRMET GDPITVIEGS PDSTIWKGQN GRTFKVGSFP ASAVTLADAG GLPATRPVHR GTPARGDQHP GSIDGDRKKA NLWDAPPARG QRRNMPLERM KGISRSLESV LSLG Highest antigen sequence indentity to the following orthologs: Rat - 76%, Mouse - 71%.

TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNK1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TNK1
Gene Accession No. Q13470
Gene Alias CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
Gene Symbols TNK1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human TNK1. Recombinant protein control fragment (Product #RP-89813).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8711
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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