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TNNI1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
$191.80 - $437.00
Specifications
Antigen | TNNI1 |
---|---|
Concentration | 0.5 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
Classification | Polyclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
FEPA5145255
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Invitrogen™
PA5145255 |
200 μL |
Each for $437.00
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FEPA5145256
|
Invitrogen™
PA5145256 |
20 μL |
Each for $191.80
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Description
Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes.Specifications
TNNI1 | |
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat, Pig | |
P13413, P19237, Q9WUZ5 | |
21952, 29388, 396947, 7135 | |
Recombinant Rat TNNI1 protein, Met1-Gln187 (Accession #P13413). | |
Primary | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
0.5 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.05% Proclin 300; pH 7.4 | |
SSTNI; TNN1 | |
TNNI1 | |
IgG | |
Protein A | |
TNNI1 |
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