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Invitrogen™ TNNI2 Polyclonal Antibody
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Catalog No. PIPA5143043
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100 μg
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PIPA5143043 100 μg
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Catalog No. PIPA5143043 Supplier Invitrogen™ Supplier No. PA5143043
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Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize both reported isoforms (NP_003273.1; NP_001139313.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNNI2
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Tnni2
Gene Accession No. P13412, P27768, P48788
Gene Alias AMCD2B; DA2B; FSSV; fsTnI; TnI; TNNI2; troponin 1, type 2; troponin I; troponin I fast twitch 2; troponin I type 2 (skeletal, fast); troponin I, fast skeletal muscle; Troponin I, fast-twitch isoform; troponin I, fast-twitch skeletal muscle isoform; troponin I, skeletal, fast; troponin I, skeletal, fast 2; troponin I2, fast skeletal type; Trp1
Gene Symbols Tnni2
Host Species Goat
Immunogen Peptide with sequence KRNRAITARRQHLKS-C (aa 6-20).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21953, 29389, 7136
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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