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Invitrogen™ TNNT1 Polyclonal Antibody
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Catalog No. PIPA542109
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100 μL
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PIPA542109 100 μL
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Catalog No. PIPA542109 Supplier Invitrogen™ Supplier No. PA542109
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Description

Rabbit Polyclonal Antibody

Peptide sequence: WIHQLESEKF DLMAKLKQQK YEINVLYNRI SHAQKFRKGA GKGRVGGRWK Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 85%.

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNNT1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TNNT1
Gene Accession No. O88346, P13805
Gene Alias ANM; AW146156; Fang2; MGC104241; NEM5; skeletal muscle slow-twitch TnT; slow skeletal muscle troponin T; ssTnT; sTnT; Tnnt1; TNT; TNTS; troponin T slow skeletal muscle type; troponin T slow type isoform sTnT1; troponin T slow type isoform sTnT2; troponin T type 1 (skeletal, slow); troponin T, slow skeletal muscle; troponin T1, skeletal, slow; troponin T1, slow skeletal type; troponin-T1, skeletal, slow; zgc:193831; zgc:193865
Gene Symbols TNNT1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human TNNT1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21955, 7138
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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