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Invitrogen™ TNNT1 Polyclonal Antibody
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Catalog No. PIPA584381
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PIPA584381 100 μL
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Catalog No. PIPA584381 Supplier Invitrogen™ Supplier No. PA584381
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: EEEEAPEEPE PVAEPEEERP KPSRPVVPPL IPPKIPEGE Highest antigen sequence indentity to the following orthologs: Rat - 95%, Mouse - 97%.

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNNT1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TNNT1
Gene Accession No. P13805
Gene Alias ANM; AW146156; Fang2; MGC104241; NEM5; skeletal muscle slow-twitch TnT; slow skeletal muscle troponin T; ssTnT; sTnT; Tnnt1; TNT; TNTS; troponin T slow skeletal muscle type; troponin T slow type isoform sTnT1; troponin T slow type isoform sTnT2; troponin T type 1 (skeletal, slow); troponin T, slow skeletal muscle; troponin T1, skeletal, slow; troponin T1, slow skeletal type; troponin-T1, skeletal, slow; zgc:193831; zgc:193865
Gene Symbols TNNT1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TNNT1. Recombinant protein control fragment (Product #RP-103332).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7138
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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