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Invitrogen™ TNNT1 Polyclonal Antibody
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Catalog No. PIPA5104190
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PIPA5104190 100 μL
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Catalog No. PIPA5104190 Supplier Invitrogen™ Supplier No. PA5104190
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TNNT1.

This gene encodes a protein that is a subunit of troponin, which is a regulatory complex located on the thin filament of the sarcomere. This complex regulates striated muscle contraction in response to fluctuations in intracellular calcium concentration. This complex is composed of three subunits: troponin C, which binds calcium, troponin T, which binds tropomyosin, and troponin I, which is an inhibitory subunit. This protein is the slow skeletal troponin T subunit. Mutations in this gene cause nemaline myopathy type 5, also known as Amish nemaline myopathy, a neuromuscular disorder characterized by muscle weakness and rod-shaped, or nemaline, inclusions in skeletal muscle fibers which affects infants, resulting in death due to respiratory insufficiency, usually in the second year. Multiple transcript variants encoding different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNNT1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TNNT1
Gene Accession No. O88346, P13805, Q7TNB2
Gene Alias ANM; AW146156; Fang2; MGC104241; NEM5; skeletal muscle slow-twitch TnT; slow skeletal muscle troponin T; ssTnT; sTnT; Tnnt1; TNT; TNTS; troponin T slow skeletal muscle type; troponin T slow type isoform sTnT1; troponin T slow type isoform sTnT2; troponin T type 1 (skeletal, slow); troponin T, slow skeletal muscle; troponin T1, skeletal, slow; troponin T1, slow skeletal type; troponin-T1, skeletal, slow; zgc:193831; zgc:193865
Gene Symbols TNNT1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TNNT1(Accession P13805), corresponding to amino acid residues E24-D74.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171409, 21955, 7138
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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