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TNNT2 Mouse anti-Human, Clone: OTI3C6, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF807957

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.Specifications
TNNT2 | |
Monoclonal | |
Unconjugated | |
TNNT2 | |
CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT | |
Mouse | |
Affinity Chromatography | |
RUO | |
7139 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI3C6 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P45379 | |
TNNT2 | |
Native troponin complex | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
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