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Invitrogen™ TNPO2 Polyclonal Antibody
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Catalog No. PIPA567176
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100 μL
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PIPA567176 100 μL
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Catalog No. PIPA567176 Supplier Invitrogen™ Supplier No. PA567176
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: QDIKPRFHKSR TVTLPHEAER PDGSEDAEDD DD Highest antigen sequence identity to the following orthologs - mouse 94%, rat 97%.

Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TNPO2
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TNPO2
Gene Accession No. O14787
Gene Alias 1110034O24Rik; AA414969; AI464345; AI852433; importin 3; IPO3; karyopherin (importin) beta 2b; karyopherin beta 2b, transportin; karyopherin beta-2b; Knpb2b; Kpnb2b; TNPO2; transportin 2; transportin 2 (importin 3, karyopherin beta 2b); transportin-2; TRN2
Gene Symbols TNPO2
Host Species Rabbit
Immunogen Recombinant Human TNPO2. Recombinant protein control fragment (Product #RP-107820).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 30000
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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