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TNPO2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 178311AP

Catalog No. 50-173-1824


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Description

Description

Probably functions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus.
Specifications

Specifications

TNPO2
0.4 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O14787, Q99LG2
IPO3, Karyopherin beta 2b, KPNB2B, TNPO2, transportin 2, TRN2
Rabbit
IgG
150 μL
-20°C
Primary
212999, 30000, 304670
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
TNPO2
Liquid
Tnpo2
TNPO2 Fusion Protein Ag12229
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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