Invitrogen™ TNRC4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA552272

Catalog No. PIPA552272

Description

Immunogen sequence: PVSAIPAALG VNGYSPVPTQ PTGQPAPDAL YPNGVHPYPA QSPAAPVDPL QQAYAGMQHY TAAYPAAYSL VAPAFPQPPA LVAQQPPPPP QQQQQQQQQQ QQQQQREGPD GCNIFIYHLP QEFTDSEILQ MFV Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 94%.

RNA-binding protein involved in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Specifications

• Antigen: TNRC4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CELF3
• Gene Alias: 4930415M08Rik; BRUNOL1; Bruno-like protein 1; CAG repeat domain; CAG repeat protein 4; CAGH4; CELF3; CELF-3; CUG-BP and ETR-3 like factor 3; CUG-BP- and ETR-3-like factor 3; CUGBP Elav-like family member 3; CUGBP, Elav-like family member 3; ELAV-type RNA-binding protein 1; ERDA4; ETR-1; Expanded repeat domain protein CAG/CTG 4; expanded repeat domain, CAG/CTG 4; RGD1563168; RNA-binding protein BRUNOL-1; Tnrc4; trinucleotide repeat containing 4; trinucleotide repeat-containing gene 4 protein; VCUGBP, Elav-like family member 3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11189
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q5SZQ8
• Gene Symbols: CELF3
• Immunogen: Recombinant protein corresponding to Human TNRC4. Recombinant protein control fragment (Product #RP-89180).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG